

Obagi Medical is a professional-grade skincare line that focuses on clinically proven formulations to address skin concerns such as pigmentation, aging, acne, and sun damage. Unlike over-the-counter skincare, Obagi Medical products often contain prescription-strength ingredients, such as hydroquinone and tretinoin, available through authorized medical professionals.
Obagi’s Nu-Derm System is widely regarded as the gold standard for treating melasma, hyperpigmentation, sun spots, and uneven skin tone. The system combines potent ingredients like 4% hydroquinone, retinoids, and exfoliants that work together to suppress melanin production, increase cell turnover, and restore skin clarity over time.
Obagi Medical offers targeted solutions for:
Hydroquinone is a skin-lightening agent that works by inhibiting tyrosinase, the enzyme responsible for melanin production. At 4% strength (prescription-only), it is particularly effective for treating dark spots, melasma, and other forms of hyperpigmentation when used under medical supervision.
Some Obagi Medical products, especially those containing 4% hydroquinone or tretinoin, require a prescription. Others, such as the Obagi-C Rx system, can be purchased through authorized providers without a prescription, though a consultation is still recommended.
Visible results typically begin to appear within 4–6 weeks, with more significant improvement seen by 12–18 weeks. Consistency and adherence to the protocol, including sun protection, are key for optimal outcomes.
Yes, but it’s essential to tailor the regimen to your individual skin type and concerns. A consultation with a licensed provider ensures the correct products and strength are used, especially for sensitive or darker skin tones to avoid irritation or rebound pigmentation.
Mild redness, peeling, dryness, and sensitivity are common during the initial "retinization" or correction phase. These side effects are temporary and indicate that the active ingredients are working. Your provider may adjust usage frequency to ease discomfort.
It’s best to stick with the full Obagi system as designed, since the products are formulated to work synergistically. Mixing in other active products could interfere with results or increase the risk of irritation unless directed by your provider.
Absolutely. Obagi treatment protocols make your skin more sensitive to the sun. Daily use of broad-spectrum SPF 30+ is non-negotiable to prevent further pigmentation and protect your results.